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House is a medical drama in which antisocial Dr. Gregory House (Hugh Laurie), who specializes in infectious disease, works with an elite team of experts to unravel diagnostic mysteries. Lacking bedside manner and dealing with his own constant physical pain, Dr. House is known for his sharp, brutally honest demeanor. Unconventional thinking and flawless instincts afford him a great deal of respect among his peers as he continually solves complicated medical puzzles in order to save lives.